EBF Focus

To Bioanalysis and Beyond!

Oratorio di San Filippo Neri
Bologna, Italy
21-22 March 2019



PDF renditions of the powerpoint presentations can be viewed and downloaded from this page by clicking the specific point on the program. The program itself can be viewed and downloaded by clicking here  

The slides will be available a.s.a.p.

Thursday 15 March 2018
15:00   Registration desk opens
16:00 18:30 YSS Science Café – How do you like it cooked? Rare or Well done

Round table discussion on the future challenges of the young bioanalysts.

The YSS Organizing Committee will moderate a discussion on how to optimize bioanalytical processes and workflows in a world of increased regulations, increased budget pressures, portfolio changes and technology developments.

More info to follow in upcoming communications from the YSS

18:30 20:00 YSS Science Café summary Complementary reception (incl. dinner buffet)
Friday 16 March 2018
07:30   Registration desk opens
08:30 08:35 Welcome and Introduction
08:35 09:00 Feedback from the Science Café
09:00 10:30 Session 1:  Alternative sampling having an impact
09:00 09:05 Sofie Velghe (University of Ghent)
Introduction to the session
09:05 09:20 Sofie Velghe (University of Ghent)
Volumetric absorptive microsampling as an alternative tool for therapeutic drug monitoring of first-generation anti-epileptic drugs.
09:20 09:35 Michele Protti (University of Bologna)
Enhanced stability and detection window of large and small molecules prohibited in sports by urine microsampling
09:35 09:50 Bas Sleumer (PRA Health Sciences)
Orexin 2: M16 and M12 – the bold and the beautiful! – Determination of a drug and metabolite M16 and M12 in rat plasma using capillary micro sampling and LC-MS/MS
09:50 10:05 Lisa Delahaye (University of Ghent)
Volumetric absorptive microsampling for the combined determination of paracetamol and its cysteine adduct
10:05 10:20 Neus Fabregat Cabello (University of Liège)
Dealing with small sample volumes and analyte levels: the case of vitamin D metabolites in aqueous humor
10:20 10:40 Poster pitch (2-minute poster pitch for posters entering the 2018 YSS Best Poster competition – participation is voluntary for each poster submission)
10:40 11:30 Coffee break and Poster Viewing
11:30 12:30 Session 2:  Overcoming Bioanalytical issues
11:30 11:45 Natalie Corden (LGC)
The Development of a 7 Analyte Method for Measuring Heroin Metabolites in Human Urine by LC-MS/MS
11:45 12:00 Snezhana Traykova (Comac Medical Ltd)
Overcoming extraction challenges of a bisphosphonate drug from human plasma utilizing an LLE with phase separation approach
12:00 12:15 Toon Babylon (UCB Biopharma)
Bridging a classic serum PK assay to Cerebrospinal Fluid: challenges in using surrogate matrices and semi-automation during assay development and validation
12:15 12:30 Barbara Marsiglia (Envigo)
Development of a LC-MS/MS bioanalytical method for the quantitation of fragrances in plasma: challenges and troubleshooting in view of validation
12:30 13:30 Lunch break
13:30 14:30 Session 3: MMM – Matrices, Molecules and Methods/part 1
13:30 13:45 Jörg Faber (A&M Labor GmbH)
Best practices for the bioanalysis of endogenous substances
13:45 14:00 Nanda Gruben (PRA Health Sciences)
Validation of an ultrasensitive Single Molecule Counting Immunoassay for determination of pharmacokinetics in a regulated environment
14:00 14:15 Estelle Cochet (Novimmune SA)
Validation of Biomarker Assays in Disease Populations: Case Study of an Inflammatory Cytokine Immunoassay in Rheumatoid Arthritis (RA)
14:15 14:30 Nikunj Tanna (Waters Corporation)
Applying small molecule workflows to large molecule assays – Quantification of IGF-I from biological matrices using LC-MS.
14:30 15:00 Tea break and announcement 2018 YSS Best Poster Prize
15:00 16:00 Session 4: MMM – Matrices, Molecules and Methods/part 2
15:00 15:15 Serge Desmoulins (Agilent Technologies)
Drug-to-Antibody Ratio Determination for Antibody-Drug Conjugates in Serum Enbaled by a Sample Preparation Platform that Automates Affinity Purification and Deglycosylation
15:15 15:30 Dan Baker (University of Hertfordshire)
Solid Phase MicroExtraction (SPME): towards in vivo sampling of tissues and organs
15:30 15:45 Maria Jadhav (Novartis AG)
Balancing neutralizing antibodies assay sensitivity and drug tolerance in the cell-based systems
15:45 16:00 Sandy Rigot (UCB Biopharma)
Hybrid immunocapture-LC-MS/MS as a powerful and challenging tool to overcome selectivity issues
16:00 16:10 Closing Remarks and Adjourn