8th EBF Young Scientist Symposium
Into the Roaring Twenties
Radisson Blu, Hasselt (Belgium) 19-20 May 2022
Agenda 8th YSS
| Day 1: Thursday 19 May 2022 | ||||
| 08:30 | Registration desk opens | |||
| 09:45 | 10:00 | Welcome and introduction to the 8th YSS | ||
| Philip Timmerman, EBF | ||||
| 10:00 | 11:00 | Session 1: Starting on a high note | ||
| 10:00 | 10:20 | Dorota Turoňová, Charles University, Czech Republic | ||
| Microsampling for cocaine analysis – the future or just a fairy tale? | ||||
| 10:20 | 10:40 | Marco Cirrincione, Unibo | ||
| Innovative DBS microfluidics-based technology for the analysis of CBD and its metabolites | ||||
| 10:40 | 11:00 | Sigrid Deprez, U-Ghent | ||
| Combined therapeutic drug monitoring of four immunosuppressants and creatinine using a single dried blood spot using the capitainer qDBS device | ||||
| 11:00 | 11:30 | Coffee break | ||
| 11:30 | 12:30 | Session 2: Diving deeper into the data | ||
| 11:30 | 11:50 | Jyotsna Kaur, LGC | ||
| Impact of automation on cut point and statistical analysis in immunogenicity | ||||
| 11:50 | 12:10 | Eniko de Jong, ICON plc | ||
| Discussion of possible interpretations of the Low Quality Control Sample determination in immunogenicity assays | ||||
| 12:10 | 12:30 | Cathy M. Jacobs, Saarland University | ||
| Adherence monitoring – Which sample matrix might be used when? | ||||
| 12:30 | 12:45 | Introduction to the 8th YSS Science Café | ||
| 12:45 | 13:45 | Lunch – tables grouped to start Science Café discussions | ||
| 13:45 | 15:30 | 8th YSS Science Cafe (Format: round table) | ||
| Pre-, during and post the Science Café, the YSS-OC wants to engage you on forging and fostering accurate and clear (scientific) communication from our industry. We will be looking at it from 2 angles: | ||||
| External = to the community we are serving, e.g. via social media … a community relying on us and that may not be fully on board with the value, details or granularity of our (scientific) communication… with re- or misinterpreting of our message, or potentially being misled. | ||||
| Internal = In the lab and with our stakeholders, within and across teams and/or organisations. The value that accurate, open and timely communication can bring to projects, individuals and teams. | ||||
| The YSS-OC will prepare a pre-meeting survey to give food-for-thought for a dynamic roundtable panel discussion during our Science Café | ||||
| 15:30 | 16:00 | Coffee break | ||
| 16:00 | 17:00 | Session 3: What if it’s not LBA or Chromatography…? | ||
| 16:00 | 16:20 | Axel Treu, Bayer AG | ||
| MALDI mass spectrometry imaging – A sharp tool for pharma research | ||||
| 16:20 | 16:40 | Sultan Ilayda Donmez, University of Reading | ||
| Dip-stick Microfluidics enable Fast 1D Counting Of Microbial Colonies And Bacteriophage Plaques | ||||
| 16:40 | 17:00 | Anna E. van Beek, Sanquin Diagnostics Services | ||
| Biomarker assays: a take on optimisation and validation in a regulated bioanalysis lab | ||||
| 17:00 | 18:30 | Session 4: Old meets young | ||
| 17:00 | 17:30 | Kyra Cowan, on behalf of the EBF | ||
| EBF Expert view Context of Use principles for biomarker assay validation and sample analysis | ||||
| 17:30 | 18:00 | Matthew Barfield, on behalf of the EBF | ||
| EBF Expert view on the changing world and future challenges for the bioanalytical community | ||||
| 18:00 | 18:30 | Open discussion on both themes | ||
| 19:00 | 19:30 | 8th YSS Patrons Cocktail Reception | ||
| 19:30 | 21:30 | 8th YSS Dinner (included in registration) | ||
| Day 2: Friday 20 May 2022 | ||||
| 09:00 | 09:30 | Feedback from the 8th YSS Science Café | ||
| 09:30 | 10:30 | (Parallel) Session 5: And what if it is chromatography? | ||
| 09:30 | 09:50 | Lea Wagmann, Saarland University | ||
| Is hydrophilic interaction liquid chromatography suitable for emergency toxicology determination of drugs in blood plasma? | ||||
| 09:50 | 10:10 | Claire Szuster, LGC | ||
| Under Pressure: Manual versus Automated Solid Phase Extraction Platforms in the BioA Lab | ||||
| 10:10 | 10:30 | Niklas Danne-Rasche, Nuvisan | ||
| Sound bioanalysis of liposomal drug-delivery systems – Implications and considerations for method valdiation processes. | ||||
| 09:30 | 10:30 | (Parallel) Session 6: And what if it is LBA? | ||
| 09:30 | 09:50 | Nadine Commandeur, Sanquin Diagnostic Services | ||
| The challenges of adapting a ready-to-use commercial kit for the measurement of a biomarker involved in underserved bleeding disorders. | ||||
| 09:50 | 10:10 | Ian de Bus, Sanquin Diagnostics Services | ||
| Development and validation of a fit-for-purpose FVII ELISA suffering from drug interference | ||||
| 10:10 | 10:25 | Manca Spendal, Novo Nordisk in collaboration with U. Copenhagen | ||
| Impact of ADA interference in PK assay: Why this is a problem and how to approach it? | ||||
| 10:25 | 10:40 | Georgina Varga, Novo Nordisk in collaboration with U. Copenhagen | ||
| Impact of ADA interference in PK assay: Gyrolab immunoassay utilizing acid dissociation as a potential solution for reducing ADA interference | ||||
| 10:30 (10:40) |
11:30 | Coffee break and Poster Viewing (can include 5 min poster pitch depending on submissions) | ||
| 11:30 | 12:30 | (Parallel) Session 7: Can things still go wrong CHROM? | ||
| 11:30 | 11:50 | Connor Walker, Quotient Sciences | ||
| When things go wrong: Normalising failure | ||||
| 11:50 | 12:10 | Katja Zeiser, Nuvisan | ||
| Diving deeper into data: investigation of a CV% issue during a biomarker study using Gyrolab | ||||
| 12:10 | 12:30 | Rosie Penford, GlaxoSmithKline | ||
| The challenges of developing and validating target engagement Biomarker assays | ||||
| 11:30 | 12:30 | (Parallel) Session 8: When sometimes things go wrong LBA/CBA… | ||
| 11:30 | 11:50 | Oscar Knight, Intertek | ||
| Development and validation of an assay for human anti-PEG antibodies. Rising to the challenge of pre-existing antibodies to PEGylated medicines. | ||||
| 11:50 | 12:10 | Open slot – the 8th YSS OC is identiying case studies to fit this session | ||
| 12:10 | 12:30 | Open slot – the 8th YSS OC is identiying case studies to fit this session | ||
| 12:30 | 13:30 | Lunch break – Poster Focus 2 | ||
| 13:30 | 14:30 | Session 9: Ending big on small | ||
| 13:30 | 13:50 | Dieter Defever, ArgenX | ||
| Case study on the implementation of capillary microsampling in non-clinical rodent studies for PK analysis – method development and qualification strategy. | ||||
| 13:50 | 14:10 | Ana C. Moran Gil, LabCorp Drug Development | ||
| Development of immunogenicity and pharmacokinetic methods using volumetric absorptive microsampling (VAMS), whole human blood and the MesoScale Discovery (MSD) and Gyrolab platforms. | ||||
| 14:10 | 14:30 | Laura Boffel, U-Ghent | ||
| Microsampling-based method for the determination of acetaminophen and four metabolites: a tool for pharmacokinetic studies | ||||
| 14:30 | 14:40 | Announcement 2022 YSS Best Poster Winner | ||
| 14:40 | 14:45 | Closing Remarks and Adjourn | ||
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