EBF Focus

8th EBF Young Scientist Symposium

Into the Roaring Twenties

Radisson Blu, Hasselt (Belgium) 19-20 May 2022

Agenda 8th YSS

Day 1: Thursday 19 May 2022
08:30 Registration desk opens
09:45 10:00 Welcome and introduction to the 8th YSS
Philip Timmerman, EBF
10:00 11:00 Session 1: Starting on a high note
10:00 10:20 Dorota Turoňová, Charles University, Czech Republic
Microsampling for cocaine analysis – the future or just a fairy tale?
10:20 10:40 Marco Cirrincione, Unibo
Innovative DBS microfluidics-based technology for the analysis of CBD and its metabolites
10:40 11:00 Sigrid Deprez, U-Ghent
Combined therapeutic drug monitoring of four immunosuppressants and creatinine using a single dried blood spot using the capitainer qDBS device
11:00 11:30 Coffee break
11:30 12:30 Session 2: Diving deeper into the data
11:30 11:50 Jyotsna Kaur, LGC
Impact of automation on cut point and statistical analysis in immunogenicity
11:50 12:10 Eniko de Jong, ICON plc
Discussion of possible interpretations of the Low Quality Control Sample determination in immunogenicity assays
12:10 12:30 Cathy M. Jacobs, Saarland University
Adherence monitoring – Which sample matrix might be used when?
12:30 12:45 Introduction to the 8th YSS Science Café
12:45 13:45 Lunch – tables grouped to start Science Café discussions
13:45 15:30 8th YSS Science Cafe (Format: round table)
Pre-, during and post the Science Café, the YSS-OC wants to engage you on forging and fostering accurate and clear (scientific) communication from our industry. We will be looking at it from 2 angles:
External = to the community we are serving, e.g. via social media … a community relying on us and that may not be fully on board with the value, details or granularity of our (scientific) communication… with re- or misinterpreting of our message, or potentially being misled.
Internal = In the lab and with our stakeholders, within and across teams and/or organisations. The value that accurate, open and timely communication can bring to projects, individuals and teams.
The YSS-OC will prepare a pre-meeting survey to give food-for-thought for a dynamic roundtable panel discussion during our Science Café
15:30 16:00 Coffee break
16:00 17:00 Session 3: What if it’s not LBA or Chromatography…?
16:00 16:20 Axel Treu, Bayer AG
MALDI mass spectrometry imaging – A sharp tool for pharma research
16:20 16:40 Sultan Ilayda Donmez, University of Reading
Dip-stick Microfluidics enable Fast 1D Counting Of Microbial Colonies And Bacteriophage Plaques
16:40 17:00 Anna E. van Beek, Sanquin Diagnostics Services
Biomarker assays: a take on optimisation and validation in a regulated bioanalysis lab
17:00 18:30 Session 4: Old meets young
17:00 17:30 Kyra Cowan, on behalf of the EBF
EBF Expert view Context of Use principles for biomarker assay validation and sample analysis
17:30 18:00 Matthew Barfield, on behalf of the EBF
EBF Expert view on the changing world and future challenges for the bioanalytical community
18:00 18:30 Open discussion on both themes
19:00 19:30 8th YSS Patrons Cocktail Reception
19:30 21:30 8th YSS Dinner (included in registration)
Day 2: Friday 20 May 2022
09:00 09:30 Feedback from the 8th YSS Science Café
09:30 10:30 (Parallel) Session 5: And what if it is chromatography?
09:30 09:50 Lea Wagmann, Saarland University
Is hydrophilic interaction liquid chromatography suitable for emergency toxicology determination of drugs in blood plasma?
09:50 10:10 Claire Szuster, LGC
Under Pressure: Manual versus Automated Solid Phase Extraction Platforms in the BioA Lab
10:10 10:30 Niklas Danne-Rasche, Nuvisan
Sound bioanalysis of liposomal drug-delivery systems – Implications and considerations for method valdiation processes.
09:30 10:30 (Parallel) Session 6: And what if it is LBA?
09:30 09:50 Nadine Commandeur, Sanquin Diagnostic Services
The challenges of adapting a ready-to-use commercial kit for the measurement of a biomarker involved in underserved bleeding disorders.
09:50 10:10 Ian de Bus, Sanquin Diagnostics Services
Development and validation of a fit-for-purpose FVII ELISA suffering from drug interference
10:10 10:25 Manca Spendal, Novo Nordisk in collaboration with U. Copenhagen
Impact of ADA interference in PK assay: Why this is a problem and how to approach it?
10:25 10:40 Georgina Varga, Novo Nordisk in collaboration with U. Copenhagen
Impact of ADA interference in PK assay: Gyrolab immunoassay utilizing acid dissociation as a potential solution for reducing ADA interference
11:30 Coffee break and Poster Viewing (can include 5 min poster pitch depending on submissions)
11:30 12:30 (Parallel) Session 7: Can things still go wrong CHROM?
11:30 11:50 Connor Walker, Quotient Sciences
When things go wrong: Normalising failure
11:50 12:10 Katja Zeiser, Nuvisan
Diving deeper into data: investigation of a CV% issue during a biomarker study using Gyrolab
12:10 12:30 Rosie Penford, GlaxoSmithKline
The challenges of developing and validating target engagement Biomarker assays
11:30 12:30 (Parallel) Session 8: When sometimes things go wrong LBA/CBA…
11:30 11:50 Oscar Knight, Intertek
Development and validation of an assay for human anti-PEG antibodies. Rising to the challenge of pre-existing antibodies to PEGylated medicines.
11:50 12:10 Open slot – the 8th YSS OC is identiying case studies to fit this session
12:10 12:30 Open slot – the 8th YSS OC is identiying case studies to fit this session
12:30 13:30 Lunch break – Poster Focus 2
13:30 14:30 Session 9: Ending big on small
13:30 13:50 Dieter Defever, ArgenX
Case study on the implementation of capillary microsampling in non-clinical rodent studies for PK analysis – method development and qualification strategy.
13:50 14:10 Ana C. Moran Gil, LabCorp Drug Development
Development of immunogenicity and pharmacokinetic methods using volumetric absorptive microsampling (VAMS), whole human blood and the MesoScale Discovery (MSD) and Gyrolab platforms.
14:10 14:30 Laura Boffel, U-Ghent
Microsampling-based method for the determination of acetaminophen and four metabolites: a tool for pharmacokinetic studies
14:30  14:40 Announcement 2022 YSS Best Poster Winner
 14:40 14:45 Closing Remarks and Adjourn